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As described by the 3rd century historian Diogenes Laertius, “sooner than trample on it [i.e., a bean field], he endured to be slain at the cross-roads by the men of Acragas.” Modern reports of favism date from the mid-19th century when some G6PD-deficient patients presented with jaundice

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The SOD1 G93A rat brain possesses increased NLRP3 and active caspase 1 levels, and this augmentation was associated with a higher NFκB expression [93]